FRONTAL LOBE DYSFUNCTION IN MENTAL ILLNESS
Target Article by Abbruzzese et al. on Frontal-Cortex

<hr> Massimo Abbruzzese, Stefano Ferri, Laura Bellodi & Silvio Scarone (1993) Frontal Lobe Dysfunction in Mental Illness. Psycoloquy: 4(09) Frontal Cortex (1)<br>Versions: <a href=ftp://www.cogsci.soton.ac.uk/pub/psycoloquy//1993.volume.4/psyc.93.4.09.frontal-cortex.1.abbruzzese>ASCII</a> <a href=http://www.cogsci.ecs.soton.ac.uk/cgi/psyc/newpsy?4.09>formatted</a><hr>
<TITLE>Psycoloquy 4(09): Frontal Lobe Dysfunction in Mental Illness</TITLE>
<H1>FRONTAL LOBE DYSFUNCTION IN MENTAL ILLNESS<br>
Target Article by Abbruzzese et al. on Frontal-Cortex<br>
</H1>
<ADDRESS>Massimo Abbruzzese, Stefano Ferri, Laura Bellodi & Silvio Scarone<br>
Psychiatric Branch<br>
Department of Biomedical and Technological Sciences<br>
University of Milan Medical School and IRCCS H S Raffaele<br>
Milano, 20127 Italy<br>
<br>
<a href=mailto:MACCIAF@IMIHSRA.bitnet>MACCIAF@IMIHSRA.bitnet</a> 
</ADDRESS>
<P><H1>Abstract</H1><BLOCKQUOTE>
Much converging evidence suggests that a specific
role is played by the dorsolateral prefrontal cortex (DLPC) in
schizophrenic disorders and by the orbitofrontal cortex (OFC) in
obsessive-compulsive disorder (OCD). In this study, 25
schizophrenic and 25 OCD patients were evaluated with the Wisconsin
Card Sorting Test and the Object Alternation Test, tests that are
sensitive to DLPC and OFC damage, respectively. The patients were
also given the Weigl Sorting Test and Word Fluency Test to assess
global frontal functioning. The results point to a DLPC deficit in
schizophrenia and an OFC lability in OCD and confirm that
functional disorders of the central nervous system can be
investigated using neuropsychological methods.
</BLOCKQUOTE>
<P><H1>Keywords</H1><i>
cognitive disorder, dorsolateral prefrontal cortex,
mental disorder, neuropsychology, obsessive-compulsive disorder,
orbitofrontal cortex, psychosis, schizophrenia.
</i>
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