Julia Rucklidge (1995) Incorporating Estrogen's Masculinizing Role
. Psycoloquy: 6(18) Sex Brain (2)
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Psycoloquy 6(18): Incorporating Estrogen's Masculinizing Role
INCORPORATING ESTROGEN'S MASCULINIZING ROLE
Commentary on Fitch & Denenberg on Sex-Brain
Julia Rucklidge
Programme in Clinical Psychology
Room 292, Education Block
2500 University Drive N.W.
University of Calgary
Calgary, Alberta, T2N-1N4
jrucklid@acs.ucalgary.ca
Abstract
The role of estrogen in differentiating the sexes may not
be as clearly defined as Fitch & Denenberg would have us believe.
Although their presentation of the feminizing role for estrogen was
intriguing, I question whether it can be so easily categorized and
wonder where the research on estrogen's masculinizing role fits
into their model.
Keywords
corpus callosum, development, estrogen, feminization,
ovaries, sensitive period.
References
- Breedlove, S.M. (1994). Sexual differentiation of the human nervous system. Annual Review of Psychology, 45, 465-488.
- Dohler, K.D., Hines, M., Coquelin, A., Davis, F., Shryne, J.E. & Gorski, R.A. (1982). Pre- and postnatal influence of diethylstilbestrol on differentiation of the sexually dimorphic nucleus in the preoptic area of the female rat brain. Neuroscience Letters, 4, 361-365.
- Ehrhardt, A.A., Meyer-Bahlburg, H.F.L., Rosen, L.R., Feldman, J.F., Veridiano, N.P., Zimmerman, I. & McEwen, B.S. (1985). Sexual orientation after prenatal exposure to exogeneous estrogen. Archives of Sexual Behavior, 14, 57-77.
- Fitch, R. H. & Denenberg, V.H. (1995). A Role for Ovarian Hormones in Sexual Differentiation of the Brain. PSYCOLOQUY 6(5) sex-brain.1.fitch.
- Hendricks, S.E. (1969). Influence of neonatally administered hormones and early gonadectomy on rats' sexual behavior. Journal of Comparative Physiology and Psychology, 69, 408-413.
- Hines, M. (1982). Prenatal gonadal hormones and sex differences in human behavior. Psychological Bulletin, 92, 56-80.
- Hines, M., Alsum, P., Roy, M., Gorski, R.A. & Goy, R.W. (1987). Estrogenic contributions to sexual differentiation in the female guinea pig: Influences of diethylstilbestrol and tamoxifen on neural, behavioral and ovarian development. Hormones and Behavior, 21, 402-417.
- Hines, M. & Collaer, M.L. (1991). Gonadal hormones and sexual differentiation of human behavior: Developments from research on endocrine syndromes and studies of brain structure. Annual Review of Sex Research, 4, 1-48.
- Hines, M. & Shipley, C. (1984). Prenatal exposure to diethylstilbestrol (DES) and the development of sexually dimorphic cognitive abilities and cerebral lateralization. Developmental Psychology, 20, 81-94.
- MacLusky, N.J., Naftolin, F. & Goldman-Rakic, P.S. (1986). Estrogen formation and binding in the cerebral cortex of the developing rhesus monkey. Proceedings of the National Academy of Science, 83, 513-516.
- MacLusky, N.J. & Naftolin, F. (1981). Sexual differentiation of the central nervous system. Science, 211, 1294-1303.
- Meyer-Bahlburg, H.F., Feldman, J.F., Cohen, P. & Ehrhardt, A.A. (1988). Perinatal factors in the development of gender-related play behavior: Sex hormones versus pregnancy complications. Psychiatry, 51, 260-271.
- Mullins, R.F. & Levine, S. (1968). Hormonal determinants during infancy of adult sexual behavior in the male rat. Physiology and Behavior, 3, 339- 343.
- Reinisch, J.M., Ziemba-Davis, D.M. & Sanders, S.A. (1991). Hormonal contributions to sexually dimorphic behavioral development in humans. Special issue: Neuroendocrine effects on brain development and cognition. Psychoneuroendocrinology, 16, 213-278.
- Schachter, S.C. (1994). Handedness in women with intrauterine exposure to diethylstilbestrol. Neuropsychologia, 32, 619-623.
- Whalen, R.E. & Nadler, R.D. (1963). Suppression of the development of female mating behavior by estradiol administration in infancy. Science, 141, 273-274.